Cincinnati improved its 2006 record at home to 12-1. The Bearcats are riding a 10-game winning streak at the UC Baseball Stadium.
Nick Maragas had his career-best six-game hit streak snapped after going 0 for 4.
Adam Yeager's fourth inning single improved his hitting streak to five straight.
UC improved to 5-1 against in-state rivals this year with the win. The Bearcats have won 17 of their last 23 games against Ohio adversaries.
Mark Muscenti moved into a tie for 11th on UC's career games played list with 188, a spot he shares with Jamie Baker (1989-92). Muscenti also improved to 14th in career at-bats (645), passing former teammate Brad Schutz.
Jon DeLuca climbs into a tie for 11th on UC's career games played list with Corey Hinton (1996-99), with both players appearing in 179 contests. DeLuca also overtook Jack Kuzniczci for 11th on the hits chart with 192.
Jack Nelson homered twice in a single game for the second time this season and the third time in his career. He also established a career-high with five RBI.