UC is 46-4 in its last 50 regular season, non-conference home games.
UC's 10-0 run to open the contest was its largest of the season to open a game. The previous best was a 9-0 run to open a 77-49 win over Appalachian State on Nov. 16. The Bearcats also did not allow Upstate to make a field goal over the first 3:30 of the game.
USC Upstate's 8-0 in the first half marked the first run of eight points or more allowed by UC this season.
The Bearcats bookended the first half with an 11-2 run over the final 3:28. Over the first 3:30 and the final 3:30 of the opening half, combined, UC outscored Upstate, 21-2.
Cincinnati's 13 three-point field goals were the most on the season and the most since connecting for 16 versus Chicago State in 2011.
The Bearcats connected for 27 free throws (on 34 attempts). The made foul shots are the most in a game since UC connected 31 times from the stripe versus Notre Dame in the 2008-09 season.
UC held USC Upstate to 50 points, marking the 14th consecutive game the Bearcats held their opponent under 70 points and 34th time in the last 36 games.
In scoring 86 points in the victory, the Bearcats are now 48-2 when scoring at least 70 points since the start of the 2010-11 season.
Cincinnati forced 22 Upstate turnovers, the fourth consecutive game in which the Bearcats have forced the opponent into 20 or more turnovers.
With 22 points, Kilpatrick now has 1,582 for his career. That total passes Jason Maxiell (1,566) for 12th place all-time at UC. Kilpatrick entered the week 11th in the nation in career scoring.
Kilpatrick also played in his 113th consecutive game, which moves him into third on the all-time list. The UC record is 131 consecutive games played, held by Keith Gregor, while Maxiell is second on that list at 129 consecutive games played.
Kilpatrick's six three-pointers gave him at least five for the second consecutive game. The only other time in his career he accomplished that feat was last season versus Marquette (1/19) and at Syracuse (1/21).
Kilpatrick's seven assists were a career high, topping a previous best of six (most recently against Kennesaw State).
Jackson saw a streak of 13 straight games with a block come to an end. His 143 career blocks are three shy of tying Rick Roberson for fifth all-time at UC.
Guyn set a career-high with 15 points. He eclipsed his previous best of 11 points against Chicago State last season.
With three three-pointers, Guyn set a new career-best. His previous mark was two, most recently against North Carolina Central on Nov. 8.
Troy Caupain's 15 points were a season-high for the freshman. He also dished out five assists for the best total in his young career.